Oh dear, why are you so uncomfortable, the ones you are afraid of are probably intimidated by you. Just find something you have in common and focus on that. Start talking to them about things they like, football or whatever and you might find a common ground instead of focusing on your differences.
This might sound stupid but one or two drinks helps loosen you up and helps you be more confident with talking to people especially if its something you are not used to. Don't make it a habit though or else you can get addicted but on special occasions like this, its okay.