You can certainly damage your hair and even pull it out when using straighteners but you cannot cause irreversible hair loss. Straightening your hair does not directly cause hair loss. The only part of the hair that is alive and growing is in the scalp, under the skin's surface.
Yes, hair transplant really works. Men and women with superior hair loss whose follicles have been inactive for 2-7 years will have bad results. According to hair transplant receiver, you will generally get back about 25% of your existing hair density.