Over the past decade, the phrase ‘cryo-electron microscopy’,often abbreviated as ‘cryo-EM’, has evolved toencompass a broad range of experimental methods. At he core, each of these is based upon the principle of imaging radiation-sensitive specimens in a transmission electron microscope under cryogenic conditions. In biology, applications of cryo-EM now cover a … Read more

The unique value of liposomes in agricultural industry is that they can be made into model as research substitute to emulate more complex natural systems. For example, in the study of plant transport processes, liposomes serve as a model system for cellular membranes to investigate protein functionality including osmotic and pH tolerance. Liposomes … Read more

he unique value of liposomes in agricultural industry is that they can be made into model as research substitute to emulate more complex natural systems. For example, in the study of plant transport processes, liposomes serve as a model system for cellular membranes to investigate protein functionality including osmotic and pH … Read more

Currently available local anesthetics have relatively short half-life, and may cause severe systemic adverse effects. This problem could be circumvented, in large part, by encapsulating drug molecules in liposomes, which allows for controlled release of the therapeutic agents. Encapsulation can also alter the spatial and temporal distribution of the drug molecules in human body resulting … Read more

A novel type of liposome, named heremultivesicular liposomes, was prepared by evaporation of organic solvents from chloroform-ether spherules suspended in water. Within each spherule were numerous water droplets that contained solutes to be trapped in liposomes upon solvent evaporation. Liposome preparations of different … Read more

Liposomes constituted from light-sensitive lipids have been explored since early 1980s. Membrane permeabilization of these light-controlled liposomes are induced upon light exposure of specific wavelength to target drug release. A successful example of photo-activated liposome formulation in clinical use now is Visudyne therapy to treat age-related macular degeneration of (AMD) in patients. In this formulation, … Read more