For most folks it would be a single sentence rather than a paragraph, "Better to remain silent and be thought a fool than to speak out and remove all doubt".
Find your passion and do it. Make your own definition of success. Surround yourself with positive people as much aa possible. As for those negative people you can't eliminate, (let's face it there is at least one in every family.) just limit your exposure to them.
Dream big, make a plan, work hard, surround yourself with exceptional people. Success is measured by the risk taken to attain it. Don't settle, find your passion and live it. Know you can.
Reverse your center of gravity,
increase your genetic deck.