Depends on what you want.
Personally I find Wyoming barren and devoid of civilization. If you like outdoor wilderness, you can find that almost anywhere else. The state is 93% white, so you're probably not going to find good sushi or pad thai. There's no significant culture. Music, art, fashion, cuisine, etc etc.
There's no jobs and the salaries are low. Not many career opportunities. Imagine the next Google or Amazon popping up in Wyoming. Because I can't. I tend to avoid places where the main industries are mineral extraction and agriculture. Bleh. The whole state is home to only half a million people. Just white, religious, and extremely conservative. I'm open to different political ideas but you'd be hard press to find different ideas in Wyoming. Much like any other rural town of the same description. But remember this is a STATE.