YOU COULD ALWAYS USE BLOCK CAPITALS.
IF THAT'S NOT ENOUGH THEY COULD BE BOLD.
WITH ITALICS ADDED.
AND AN UNDERLINE FOR EMPHASIS.
There's a Hollywood legend that an actor refused to grow a beard for a role, even though his director insisted on it. He said, "I'll ACT the beard." You can take an idea from C.S.Lewis and write in such a way that the font SEEMS larger.
And good morning to you, Teach. :)